Article

Estrogen Receptor Variant ER-α36 Facilitates Estrogen Signaling Via EGFR Signaling in Glioblastoma

2022-01-31

Abstract excerpt

<title>Abstract</title> <p>Glioblastoma is a deadly and common primary brain tumor. Poor prognosis is linked to high proliferation and cell heterogeneity. Sex differences may play a role in patient outcome. Previous studies showed that ER-α36, a variant of the estrogen receptor, mediated non-genomic estrogen signaling and is highly expressed in many ER-negative tumors. ER-α36 also associates with the EGFR. We sho...

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Literature Corpus work: e172a3e9-dbb1-5b4c-8e04-87a2b32a2f56
DOI: 10.21203/rs.3.rs-856938/v2

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