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Article

Clinical phenotype predicts anti-PLA2R serology in nephrotic range proteinuria.

Nefrologia - 1 Jan 2026

Demirezen Asil, Malkoç Nuri Alperen, Tomar Veysel Baran, Çetin Taha Enes, Akçay Ömer Faruk, Türkmen Sena, Gülbahar Özlem, Öğüt Betül, Işık Gönül İpek, Güz Galip, Derici Ülver, Erten Yasemin, Altok Kadriye, Helvacı Özant

Abstract excerpt

BACKGROUND: The 2021 KDIGO guidelines permit non-invasive diagnosis of membranous nephropathy using anti-PLA2R antibodies in patients with nephrotic syndrome. However, optimal patient selection for anti-PLA2R testing remains undefined, particularly in patients with nephrotic-range proteinuria without nephrotic syndrome. METHODS: We conducted a retrospective analysis of 156 consecutive patients with...

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PMID: 42618194
DOI: 10.1016/j.nefroe.2026.501529

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