Article
Compensatory molecular evolution of HC-Pro, an RNA-silencing suppressor from a plant RNA virus.
Molecular biology and evolution - 1 Mar 2010
Torres-Barceló Clara, Daròs José-Antonio, Elena Santiago F
Abstract excerpt
RNA silencing is a eukaryotic mechanism involved in several cellular processes, one example being a sequence-specific antiviral defense. Many plant viruses have developed counterdefensive proteins that in many instances are multifunctional, such as helper component protease (HC-Pro) of Tobacco etch virus (TEV). In a previous work, a collection of mutants with amino acid replacements in TEV HC-Pro was generated,...
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