Article
Generation of an Attenuated, Cross-Protective Pepino mosaic virus Variant Through Alignment-Guided Mutagenesis of the Viral Capsid Protein.
Phytopathology - 1 Jan 2015
Chewachong Godwill M, Miller Sally A, Blakeslee Joshua J, Francis David M, Morris T Jack, Qu Feng
Abstract excerpt
Mild variants of many viruses are able to protect infected plants from subsequent invasion by more severe variants of the same viruses through a process known as cross-protection. In the past, the cross-protective viral variants were commonly derived from mild field isolates that were sometimes genetically heterogeneous, providing variable levels of cross-protection. Here, we report a novel approach to rapidly...
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