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Article

Exploring the shared genetic architecture between post-traumatic stress disorder (PTSD) and obstructive sleep apnea (OSA).

European journal of psychotraumatology - 1 Dec 2026

Liu Xi, Liu Yangyang, Gao Mengyu, Lu Jinxin, Lu Dengfeng, Song Zhaoming, Wang Menghan, Song Bingyi, Li Haiying, Qiu Youjia, Wang Zhong

Abstract excerpt

Background: Observational research has revealed an association between post-traumatic stress disorder (PTSD) and obstructive sleep apnea (OSA), but their shared genetic architecture remains unclear. This study aimed to characterise their shared genetic architecture and evaluate potential causal relationships.Methods: Genome-wide association study (GWAS) summary statistics for PTSD and OSA were analyzed. Genetic...

Topics

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Bayes Theorem
Genetic Predisposition to Disease
Genome-Wide Association Study
Linkage Disequilibrium
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sleep Apnea, Obstructive

Stress Disorders, Post-Traumatic

Source

Open in PubMed Open full text

Identifiers

PMID: 42611531
DOI: 10.1080/20008066.2026.2709174
PMCID: PMC13487852

Genes

TMEM106B
TRAF3
EFCAB5
TRIM72

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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