A novel adrenomedullin receptor signaling-based prognostic model predicts immunosuppressive microenvironment and informs therapeutic stratification in hepatocellular carcinoma: A retrospective bioinformatics study.

Abstract excerpt

The adrenomedullin receptor signaling pathway plays a crucial role in tumor progression, yet its comprehensive implication in hepatocellular carcinoma (HCC) remains underexplored. This study aimed to develop and validate a multi-gene prognostic signature based on adrenomedullin receptor signaling-related genes (ARGs) and to elucidate its associations with clinicopathological features, immune microenvironment,...

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