Selective taste impairment in relapsing-remitting Multiple Sclerosis and Supervised Learning - driven diagnostic classification.

doi:10.1016/j.msard.2026.107420

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Article

Selective taste impairment in relapsing-remitting Multiple Sclerosis and Supervised Learning - driven diagnostic classification.

Multiple sclerosis and related disorders - 1 Oct 2026

Melis Melania, Naciri Lala Chaimae, Mastinu Mariano, Deligia Silvia, Diana Daniela, Idini Elisa, Coghe Giancarlo, Frau Jessica, Crnjar Roberto, Sollai Giorgia, Cocco Eleonora, Tomassini Barbarossa Iole

Abstract excerpt

Taste disturbances have been largely overlooked in Multiple Sclerosis (MS), despite mounting evidence that neuroinflammation and demyelination may disrupt chemosensory pathways. This study investigated taste perception in People with MS (PwMS) compared with healthy controls (HCs), explored whether specific taste-related features could classify MS using Supervised Learning (SL), and examined associations with...

Read the complete abstract on PubMed

Topics

Humans
Female
Male
Adult
Multiple Sclerosis, Relapsing-Remitting

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Supervised Machine Learning

Taste Disorders

Taste Perception

Middle Aged

Receptors, G-Protein-Coupled

Classification Algorithms

Taste Receptors, Type 2

Boosting Machine Learning Algorithms

Polymorphism, Single Nucleotide

Taste Threshold

Source

Open in PubMed

Identifiers

PMID: 42570510
DOI: 10.1016/j.msard.2026.107420

Genes

TAS1R2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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