Article
Low sRAGE Level is Associated with Increased Future Exacerbation Risk in Mild-to-Moderate COPD and Patients with Chronic Bronchitis Symptoms.
International journal of chronic obstructive pulmonary disease - 1 Jan 2026
Zhang Yutian, Ran Bi, Wang Hao, Zhou Dianmei, Zi Kai, Zeng Zijian, Yan Xi, Wang Tao, Chen Lei, Ye Tao, Jones Paul, Chen Jun, Wen Fuqiang
Abstract excerpt
Background: Early identification of patients at high-risk for exacerbation in mild-to-moderate chronic obstructive pulmonary disease (COPD), particularly those with chronic bronchitis (CB) phenotype exhibiting worse outcomes, is critical for slowing lung function decline and reducing the subsequent healthcare burden. While the soluble receptor for advanced glycation end products (sRAGE) correlates with emphysema...
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