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Article

Persistently low blood eosinophils identify a high-risk phenotype in COPD.

BMC pulmonary medicine - 25 Feb 2026

Zhang Wen, Chew Si Yuan, He Xiaoli, Wu Yanlin, Koh Mariko Siyue, Wang Guansong, Xu Zhi, Tiew Pei Yee

Abstract excerpt

BACKGROUND: Blood eosinophil count (BEC) is used to guide COPD therapy, yet its longitudinal stability and prognostic relevance remain debated. We investigated BEC variability and the clinical implications of eosinophil trajectories. METHODS: Stable COPD patients (n = 471) were prospectively recruited in Singapore from 2013 to 2025. BEC stability was assessed using paired baseline and 1-year measurements....

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Identifiers

PMID: 41742158
DOI: 10.1186/s12890-026-04202-5
PMCID: PMC13041083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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