Article
Endotype-driven prediction of acute exacerbations in chronic obstructive pulmonary disease (EndAECOPD): protocol for a prospective cohort study.
BMJ open - 4 Nov 2019
Xiao Wei, Du Long-Yi, Mao Bing, Miao Ti-Wei, Fu Juan-Juan
Abstract excerpt
INTRODUCTION: Current strategies for the prevention of acute exacerbations in chronic obstructive pulmonary disease (COPD) are primarily based on clinical measurements but fail to target the pathophysiological mechanisms, namely endotypes, of the disease. Studies identifying endotypes underlying...
Topics
- Adult
- Aged
- Aged, 80 and over
- Biomarkers
- China
- Comorbidity
- Disease Progression
- Genetic Variation
- Humans
- Inflammation Mediators
- Microbiota
- Middle Aged
- Phenotype
- Prospective Studies
- Pulmonary Disease, Chronic Obstructive
- RNA, Ribosomal, 16S
- Research Design
- Spirometry