Article
The high-risk B-to-E transitional phenotype: a prospective multi-centre validation of patient reclassification under the updated GOLD 2026 criteria.
Journal of global health - 17 Jul 2026
Zhang Boyan, Zeng Junhao, Zeng Huihui, Dai Zhongshang, Chen Yan
Abstract excerpt
Background: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2026 criteria lowered the threshold for classifying Group E to ≥1 moderate or severe acute exacerbation in the last year. However, the scale of patient reclassification and its clinical justification in real-world settings have not been validated. Methods: We utilised a prospective, multi-centre Chinese chronic obstructive pulmonary...
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