Article
The chronic bronchitic phenotype of COPD: an analysis of the COPDGene Study.
Chest - 1 Sept 2011
Kim Victor, Han MeiLan K, Vance Gwendolyn B, Make Barry J, Newell John D, Hokanson John E, Hersh Craig P, Stinson Douglas, Silverman Edwin K, Criner Gerard J
Abstract excerpt
BACKGROUND: Chronic bronchitis (CB) in patients with COPD is associated with an accelerated lung function decline and an increased risk of respiratory infections. Despite its clinical significance, the chronic bronchitic phenotype in COPD remains poorly defined. METHODS: We analyzed data from subjects enrolled in the Genetic Epidemiology of COPD (COPDGene) Study. A total of 1,061 subjects with GOLD (Global...
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