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Article

Associations Between Domestic Water Hardness, Genetic Risk and Severe MASLD: A Large-Scale Cohort Study.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 15 Aug 2026

Zhao Xiaoyu, Gui Zihao, He Houde, Yang Mengyuan, Lin Yijun, Shen Jie, Wang Ningjian, Wan Heng, Tian Feng

Abstract excerpt

This study aims to investigate the association between domestic water hardness and the risk of severe metabolic dysfunction-associated steatotic liver disease (MASLD) and to assess the potential modifying role of genetic susceptibility. The UK Biobank is a prospective cohort study that recruited over 500,000 participants across the United Kingdom between 2006 and 2010. Domestic water hardness was assessed based...

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Identifiers

PMID: 42541335
DOI: 10.1096/fj.202601814RR
PMCID: PMC13428296

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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