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Domestic water hardness, genetic risk, and distinct phenotypes of cardiovascular disease.

Environmental health : a global access science source - 14 Mar 2025

Tian Feng, Yu Genfeng, Yang Mengyuan, Sun Ying, Gui Zihao, Zhao Xiaoyu, Wang Ningjian, Wan Heng, Peng Xuetao

Abstract excerpt

AIMS: The study aimed to investigate the association between domestic water hardness and the incidence of AF and the interaction effects between water hardness and genetic susceptibility to incident AF risk. As a secondary objective, its associations with incident heart failure (HF), coronary heart disease (CHD), and stroke were measured. METHODS: The UK Biobank is a prospective cohort study comprising over...

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Cardiovascular Diseases
Drinking Water
Genetic Predisposition to Disease
Incidence

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PMID: 40087673
DOI: 10.1186/s12940-025-01166-7
PMCID: PMC11907801

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