Article
ESR1 and PIK3CA Polymorphisms as Potential Genetic Susceptibility Markers for Breast Cancer Risk in Bangladeshi Women: A Case-Control Study.
Human mutation - 1 Jan 2026
Chowdhury Mahim Hassan, Shaolin Faria Billal, Khusbu Nishat Tabassum, Puja Upama Gope, Hossain Md Sharif, Islam Md Robiul, Majumder Akash, Hassan Shah Musallin, Bhuiyan Mohiuddin Ahmed, Haque Md Aminul
Abstract excerpt
Breast cancer (BC) is one of the most common and deadly cancers affecting women worldwide. This study is aimed at investigating the association between BC risk and two single nucleotide polymorphisms (SNPs): ESR1 (rs2234693) and PIK3CA (rs6443624) in a Bangladeshi population. A case-control study was conducted with 112 BC patients and 124 healthy controls (HCs). Genomic DNA was extracted from peripheral blood...
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