Evaluation of ERCC4 (XPF) gene rs6498486 polymorphism and its potential role in breast cancer risk among Bangladeshi women.

doi:10.1186/s12885-026-15739-3

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Evaluation of ERCC4 (XPF) gene rs6498486 polymorphism and its potential role in breast cancer risk among Bangladeshi women.

BMC cancer - 17 Feb 2026

Hossain Iffat, Ivy Sanjida Chowdhury, Islam Mohammad Safiqul, Shahriar Mohammad

Abstract excerpt

This research aims to evaluate the polymorphism of the ERCC4 (XPF) gene (rs6498486) and explore its potential association to breast cancer development in women of Bangladesh, may contribute to design the screening programs for risk estimation, and to design target-based and cost-efficient treatment for the management of the disease. DNA was extracted from blood samples collected from 150 breast cancer patients...

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PMID: 41699509
DOI: 10.1186/s12885-026-15739-3
PMCID: PMC13020121

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ERCC4

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