Cardiorenal-metabolic phenotypes and risks of mortality and cardiovascular outcomes in type 2 diabetes: a retrospective cohort study.

doi:10.1016/j.diabres.2026.113472

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Article

Cardiorenal-metabolic phenotypes and risks of mortality and cardiovascular outcomes in type 2 diabetes: a retrospective cohort study.

Diabetes research and clinical practice - 1 Sept 2026

Ding Jianzhong, Kong Laixi, Zhou Rui, Zhang Jiquan, Jiang Yifan, Zeng Youcong, Zhang Siming, Wu Jijun, Zhong Xiaoli

Abstract excerpt

AIMS: To examine whether a transparent, rule-based cardiorenal-metabolic classification distinguished mortality and cardiovascular outcome patterns among adults with type 2 diabetes (T2D). METHODS: This retrospective cohort included 61,250 adults with T2D from Hong Kong DM2016. Three phenotypes were defined from baseline cardiorenal burden and hypertension: lower-risk metabolic, hypertensive metabolic, and...

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PMID: 42532346
DOI: 10.1016/j.diabres.2026.113472

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