Article
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.
Nature genetics - 1 Jun 2011
Kato Norihiro, Takeuchi Fumihiko, Tabara Yasuharu, Kelly Tanika N, Go Min Jin, Sim Xueling, Tay Wan Ting, Chen Chien-Hsiun, Zhang Yi, Yamamoto Ken, Katsuya Tomohiro, Yokota Mitsuhiro, Kim Young Jin, Ong Rick Twee Hee, Nabika Toru, Gu Dongfeng, Chang Li-Ching, Kokubo Yoshihiro, Huang Wei, Ohnaka Keizo, Yamori Yukio, Nakashima Eitaro, Jaquish Cashell E, Lee Jong-Young, Seielstad Mark, Isono Masato, Hixson James E, Chen Yuan-Tsong, Miki Tetsuro, Zhou Xueya, Sugiyama Takao, Jeon Jae-Pil, Liu Jian Jun, Takayanagi Ryoichi, Kim Sung Soo, Aung Tin, Sung Yun Ju, Zhang Xuegong, Wong Tien Yin, Han Bok-Ghee, Kobayashi Shotai, Ogihara Toshio, Zhu Dingliang, Iwai Naoharu, Wu Jer-Yuarn, Teo Yik Ying, Tai E Shyong, Cho Yoon Shin, He Jiang
Abstract excerpt
We conducted a meta-analysis of genome-wide association studies of systolic (SBP) and diastolic (DBP) blood pressure in 19,608 subjects of east Asian ancestry from the AGEN-BP consortium followed up with de novo genotyping (n = 10,518) and further replication (n = 20,247) in east Asian samples. We identified genome-wide significant (P < 5 × 10(-8)) associations with SBP or DBP, which included variants at four new...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.