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Integrative Genomic and Transcriptomic Analysis Identifies BAX as a Prognostic Marker of Disease Progression in Prostate Cancer.

Genes - 15 Jul 2026

Shih You-Cheng, Chang Chi-Fen, Huang Chao-Yuan, Yu Chia-Cheng, Lin Victor C, Lu Te-Ling, Huang Shu-Pin, Bao Bo-Ying

Abstract excerpt

Background/Objectives: Prostate cancer is one of the most common malignancies among men worldwide, and clinical outcomes following androgen deprivation therapy (ADT) vary considerably. Given that endoplasmic reticulum (ER) stress and the unfolded protein response mediate processes such as apoptosis, tumor adaptation, and disease progression, we aimed to investigate whether genetic variants in ER stress-related...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42510844
DOI: 10.3390/genes17070804
PMCID: PMC13409293

Genes

BAX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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