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HSF1 is a novel prognostic biomarker in high-risk prostate cancer that correlates with ferroptosis

23 Jun 2023

Abstract excerpt

BACKGROUND: Prostate cancer (PC) is the most common cancer in older men in Europe and the United States and has the second highest death rate among male cancers. The transcription of heat shock proteins by Heat shock factor 1 (HSF1) is known to regulate cell growth and stress. Nevertheless, the impact of HSF1 on ferroptosis in PC through heat shock protein 10 (HSPE1) remains unexplored. METHODS: This study...

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PMID: 37351671
DOI: 10.1007/s12672-023-00715-1

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