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Article

The Role of Stress Proteins in Prostate Cancer

1 Jun 2007

Abstract excerpt

The development of therapeutic resistance, after hormone or chemotherapy for example, is the underlying basis for most cancer deaths. Exposure to anticancer therapies induces expression of many stress related proteins, including small heat shock proteins (HSPs). HSPs interact with various client proteins to assist in their folding and enhance the cellular recovery from stress, thus restoring protein homeostasis...

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PMID: 18645594
DOI: 10.2174/138920207781386951

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