Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CFTR and ClC-3 Transport Fluoride Differently and Cause Dental Fluorosis in Different Ways.

Biomolecules - 3 Jul 2026

Zhang Yanli, Mao Songya, Wen Xuan, Liu Zhenxia, Hao Ying, Duan Xiaohong

Abstract excerpt

Dental fluorosis (DF) is a common endemic disease that damages dental enamel. Traditionally, DF has been attributed to environmental fluoride overload. Accumulating evidence has demonstrated that genetic factors also modulate individual susceptibility. No dedicated fluoride ion channels have been identified in mammalian cells; fluoride uptake is believed to occur mainly through passive diffusion of HF and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chloride Channels
Share to Cystic Fibrosis Transmembrane Conductance Regulator

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorides

Share to CFTR gene

Share to Polymorphism, Single Nucleotide

Share to Zebrafish

Source

Open in PubMed Open full text

Identifiers

PMID: 42509776
DOI: 10.3390/biom16070982
PMCID: PMC13406507

Genes

CFTR
CLCN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CFTR and ClC-3 Transport Fluoride Differently and Cause Dental Fluorosis in Different Ways.PMID 42509776Read ↗

Effects of SNPs in SOD2 and SOD3 interacted with fluoride exposure on the susceptibility of dental fluorosis.Semantic proximity Read ↗

Fluoride’s Effects on the Formation of Teeth and Bones, and the Influence of GeneticsSemantic proximity Read ↗

Molecular basis of fluoride toxicities: Beyond benefits and implications in human disordersSemantic proximity Read ↗

Progress of Signaling Pathways, Stress Pathways and Epigenetics in the Pathogenesis of Skeletal FluorosisSemantic proximity Read ↗

Functional evaluation of Dent’s disease-causing mutations: implications for ClC-5 channel trafficking and internalizationSemantic proximity Read ↗

Effects of enamel matrix genes on dental caries are moderated by fluoride exposures.Semantic proximity Read ↗

Fluoride export is required for competitive fitness of pathogenic microorganisms in dental biofilm modelsSemantic proximity Read ↗

Genome-wide association scan for childhood caries implicates novel genes.Semantic proximity Read ↗

Insights into <italic>AQP5</italic> Polymorphism and Genetic Associations in Molar Incisor Hypomineralization and Dental Fluorosis.Semantic proximity Read ↗

Fine-mapping of 5q12.1-13.3 unveils new genetic contributors to caries.Semantic proximity Read ↗

Fine mapping of dental fluorosis quantitative trait loci in mice.Semantic proximity Read ↗

The association between Dental Fluorosis and COL1A2 gene polymorphism among a Tunisian Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.