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Article

Brain imaging traits and epilepsy: Unraveling causal links via mendelian randomization.

Brain and behavior - 1 Oct 2024

Li Fangyan, Tang Maowen, Hao Cheng, Yang Menghua, Pan Yue, Lei Pinggui

Abstract excerpt

BACKGROUND: Epilepsy, a complex neurological disorder, is closely linked with structural and functional irregularities in the brain. However, the causal relationship between brain imaging-derived phenotypes (IDPs) and epilepsy remains unclear. This study aimed to investigate this relationship by employing a two-sample bidirectional Mendelian randomization (MR) approach. METHODS: The analysis involved 3935...

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Brain
Epilepsy
Genome-Wide Association Study
Magnetic Resonance Imaging
Mendelian Randomization Analysis

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PMID: 39350628
DOI: 10.1002/brb3.70051
PMCID: PMC11442987

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