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Article

Causal effects of lung function on brain cortical and subcortical structure: a two-sample univariable and multivariable Mendelian Randomization study.

Journal of affective disorders - 15 May 2026

You Hongtao, Huang Chaojuan, Fan Ligang, Feng Xingliang, Zhang Yuyang, Shao Naiyuan

Abstract excerpt

BACKGROUND: Lung function has been increasingly linked to brain health, prompting investigation into the causal relationships between lung function and brain structures. This study employs Mendelian Randomization (MR) to explore these causal relationships, leveraging genetic variants as proxies to predict the effects of lung function on brain cortical and subcortical structures. METHODS: We conducted univariable...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41621450
DOI: 10.1016/j.jad.2026.121238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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