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Article

Novel insights into the disease transcriptome of human diabetic glomeruli and tubulointerstitium

4 May 2020

Abstract excerpt

BACKGROUND: Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, affecting ∼30% of the rapidly growing diabetic population, and strongly associated with cardiovascular risk. Despite this, the molecular mechanisms of disease remain unknown. METHODS: RNA sequencing (RNAseq) was performed on paired, micro-dissected glomerular and tubulointerstitial tissue from patients diagnosed with DN [n...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32853351
DOI: 10.1093/ndt/gfaa121

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