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Article

Three Rare Cases of Pulmonary Squamous Cell Carcinoma Harboring a KRAS Mutation, Including the Actionable G12C Variant.

Pathology international - 1 Jul 2026

Ohba Daiji, Hiratsuka Masafumi, Ninomiya Hironori

Abstract excerpt

KRAS mutations are far less frequent in lung squamous cell carcinoma than in adenocarcinoma. In our institutional series of 136 pulmonary squamous cell carcinomas analyzed using Oncomine Dx Target Test, KRAS G12C mutations were identified only one case (0.8%). Although rare, identification of KRAS G12C mutations in LUSC may expand therapeutic options and support the role of comprehensive molecular profiling in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42464637
DOI: 10.1111/pin.70148
PMCID: PMC13376999

Genes

KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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