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Article

Proteomic Analysis Identifies Potential Biomarkers of ELOC -Mutated Renal Cell Carcinoma.

The American journal of surgical pathology - 1 Oct 2026

Fukagawa Akihiko, Arai Yasuhito, Maeshima Akiko, Hama Natsuko, Totoki Yasushi, Nakamura Hiromi, Saito-Adachi Mihoko, Hokazono Yukio, Nakamura Eijiro, Matsui Yoshiyuki, Adachi Shungo, Hamamoto Ryuji, Ushiku Tetsuo, Yachida Shinichi, Shibata Tatsuhiro

Abstract excerpt

ELOC -mutated renal cell carcinoma (RCC) is a rare tumor with only ∼40 cases reported to date; it shares a molecular background with clear cell RCC (ccRCC) in terms of hypoxia-inducible factor-alpha (HIF-α) protein accumulation. ELOC -mutated RCC is characterized by prominent leiomyomatous stromal growth and a more indolent clinical course compared with ccRCC. In our previous study, whole-genome sequencing of 102...

Read the complete abstract on PubMed

Topics

Humans
Carcinoma, Renal Cell
Kidney Neoplasms
Biomarkers, Tumor
Proteomics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Mutation

Immunohistochemistry

Male

Female

Aged

Middle Aged

Sortilin

Predictive Value of Tests

Adult

Adaptor Proteins, Vesicular Transport

Japan

Elongin

Source

Open in PubMed Open full text

Identifiers

PMID: 42438270
DOI: 10.1097/PAS.0000000000002583
PMCID: PMC13577233

Genes

ELOC
SCIN
SORT1
NAPRT
QPRT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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