Article
ELOC-mutant renal cell carcinoma: practical diagnostic features and differential considerations.
Journal of clinical pathology - 19 Mar 2026
Lin Meifang, Chen Chuncheng, Guo Shujing, Wu Yue, Lin Fenglian, Ding Xin
Abstract excerpt
AIMS: ELOC (TCEB1)-mutant renal cell carcinoma (RCC) is a recently recognised entity in the 2022 WHO classification. Due to overlapping features, it is frequently misdiagnosed as clear cell RCC (CCRCC). This study characterises the clinicopathological, immunohistochemical and molecular features of six ELOC-mutant RCCs to aid in their diagnostic distinction. METHODS: Twenty-eight RCCs initially diagnosed as CCRCC...
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