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Article

Real-World Genomic Characteristics and Prognostic Association in Advanced Papillary Thyroid Carcinoma.

JCO precision oncology - 1 Jul 2026

Toda Soji, Hiroshima Yukihiko, Iwasaki Hiroyuki, Kadoya Mei, Suzuki Chihiro, Yamazaki Haruhiko, Okubo Yoichiro, Saito Aya, Masudo Katsuhiko

Abstract excerpt

PURPOSE: Most thyroid cancers are initiated by alterations activating the mitogen-activated protein kinase (MAPK) pathway and progress via additional genomic events. Because papillary thyroid carcinoma (PTC) generally has a favorable prognosis and rarely advances, knowledge about later-acquired genomic alterations and their impact on prognosis is limited. MATERIALS AND METHODS: This study is a real-world database...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42430694
DOI: 10.1200/PO-25-00520

Genes

BRAF
TERT
AKT1
CDKN2A
NRAS
NTRK1
PTEN
RBM10
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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