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Article

Clinical actionability of molecular testing in advanced thyroid cancer: a real-world cohort study.

European thyroid journal - 1 Jun 2026

Changoer Prashant, van Houten Pepijn, Ceruti Daniele, van Engen-van Grunsven Ilse, Walraven Janneke E W, Ottevanger Petronella B, Jaeger Martin, Netea-Maier Romana T

Abstract excerpt

Objectives: Molecular testing is increasingly used in thyroid cancer (TC) to complement diagnostics and guide systemic therapy choices. However, real-world data on its clinical impact remain limited. We evaluated the molecular landscape, clinical actionability, and outcomes of matched therapy in patients with advanced TC. Methods: We retrospectively assessed 103 patients with advanced TC who underwent panel-based...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42258399
DOI: 10.1530/ETJ-26-0074
PMCID: PMC13292826

Genes

BRAF
RET
NRAS
PTEN
TP53

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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