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Article

Genetic variants in the ITGB6 gene is associated with the risk of radiation pneumonitis in lung cancer patients treated with thoracic radiation therapy.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2016

Yi Minxiao, Tang Yang, Liu Bo, Li Qianxia, Zhou Xiao, Yu Shiying, Fu Shengling, Cai Yixin, Yuan Xianglin

Abstract excerpt

The αvβ6 integrin is a cell surface adhesion molecule that plays critical roles in the injury and inflammation processes. We hypothesized that polymorphisms in αvβ6 integrin genes (ITGAV and ITGB6) might be associated with the risk of radiation pneumonitis (RP) in lung cancer patients treated with thoracic radiation. We genotyped three potentially functional αvβ6 integrin single-nucleotide polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26449830
DOI: 10.1007/s13277-015-4171-y

Genes

ITGB6
ITGAV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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