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Article

Genetic mutations in neuroendocrine carcinomas of unknown primary.

Otolaryngologia polska = The Polish otolaryngology - 16 Jun 2026

Nagano Hiromi, Kiyama Satoshi, Takayuki Kyutoku, Yamashita Masaru

Abstract excerpt

<p><strong>Introduction: </strong>Although genetic mutations have been reported in neuroendocrine carcinomas of unknown primary (NECs-UP), no scientifically validated targeted therapies are currently available. Moreover, cancer genomic profiling tests remain underutilized in clinical practice. These issues highlight the urgent need to elucidate the genomic landscape of NECs-UP and its potential...

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Identifiers

PMID: 42417420
DOI: 10.5604/01.3001.0055.7748

Genes

CIC
CAT
RICTOR
SDHA
SPEN
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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