Article
Novel Analysis Methods to Mine Immune-Mediated Phenotypes and Find Genetic Variation Within the Electronic Health Record (Roadmap for Phenotype to Genotype: Immunogenomics).
The journal of allergy and clinical immunology. In practice - 1 Jul 2022
Krantz Matthew S, Kerchberger V Eric, Wei Wei-Qi
Abstract excerpt
The field of immunogenomics has the opportunity for accelerated genetic discovery aided by the maturation of electronic health records (EHRs) linked to DNA biobanks. Novel analysis methods in deep phenotyping of EHR data allow the full realization of the paired and increasingly dense genetic/phenotypic information available. This enables researchers to uncover genetic risk factors for the prevention and optimal...
Topics
- Electronic Health Records
- Genetic Variation
- Genotype
- Humans
- Phenotype