Article
Helicobacter pylori outer membrane protein Q allele distribution is associated with distinct pathologies in Pakistan.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2016
Yakoob Javed, Abbas Zaigham, Khan Rustam, Salim Saima Azhar, Awan Safia, Abrar Ambar, Jafri Wasim
Abstract excerpt
Helicobacter pylori (H. pylori) strains expressing outer membrane protein Q (HopQ) promote adherence to the gastric epithelial cell. We characterized HopQ alleles in relation to H. pylori-related disease, histology and virulence markers. Gastric biopsies were obtained at esophagogastroduodenoscopy from patients with upper gastrointestinal symptoms. H. pylori culture, histology and polymerase chain reaction (PCR)...
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