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Article

Mendelian Randomization Analysis of the Inflammatory Factor CXCL5 and Type 2 Diabetes Mellitus.

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2026

Li Jiaxin, Li Xing, Li Yuan, Zhou Ning, Yi Huijuan, Fan Qi, Wang Bo, Tian Yushi, Ni Xiuqin

Abstract excerpt

INTRODUCTION: This study focused on investigating the causal relationship between inflammatory factors and Type 2 Diabetes Mellitus (T2DM) and identifying metabolites associated with inflammatory factors as potential mediators. METHODS: Mendelian Randomization (MR) analysis was conducted using pooled genome-wide association study data to genetically predict T2DM. The study was registered under the identifier...

Read the complete abstract on PubMed

Topics

Humans
Diabetes Mellitus, Type 2
Mendelian Randomization Analysis
Chemokine CXCL5
Genome-Wide Association Study
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Inflammation Mediators

Polymorphism, Single Nucleotide

Risk Factors

Case-Control Studies

Source

Identifiers

PMID: 42393900
DOI: 10.2174/0118715303453894260611104028

Genes

CXCL5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

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