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Syncytia Formation in the Pathogenesis of SARS-CoV-2 Infection: Lessons from Viral Infections.

Viral immunology - 1 Aug 2026

Tafazoli Aida, Dowran Razieh

Abstract excerpt

It is widely known that numerous enveloped viruses can produce multinucleated cells (syncytia) as a result of viral entry-related membrane fusion events. By protecting the virus from the host's immune reaction, these syncytia are thought to promote viral reproduction. Syncytia are collections of merged cells. A viral spike protein (S) on the surface of an infected cell interacts with receptors on nearby cells to...

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PMID: 42376837
DOI: 10.1177/08828245261433819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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