Article
A novel relationship between time offsets in capillary electrophoresis and DNA sequence variations in short tandem repeats.
Journal of forensic sciences - 1 Sept 2026
Johnson Damani, Curran James, Kalafut Tim
Abstract excerpt
Next-generation sequencing (NGS) provides increased discriminatory power in forensic DNA analysis due to the detection of isoalleles. Differences in sequences between alleles allow for a second layer of differentiation between DNA contributors beyond the number of short tandem repeat (STR) repeat units. However, because NGS is a more time and resource-intensive analysis than conventional capillary electrophoresis...
Read the complete abstract on PubMedTopics
- Electrophoresis, Capillary
- Microsatellite Repeats
- Humans
- DNA Fingerprinting
- High-Throughput Nucleotide Sequencing
- Sequence Analysis, DNA
