Article
Modeling allelic analyte signals for aSTRs in NGS DNA profiles.
Journal of forensic sciences - 1 Jul 2021
Cheng Kevin, Lin Meng-Han, Moreno Lilliana, Skillman Jessica, Hickey Stephanie, Cuenca Daniela, Hudlow William R, Just Rebecca, Bright Jo-Anne, Buckleton John, Curran James M
Abstract excerpt
We describe an adaption of Bright et al.'s work modeling peak height variability in CE-DNA profiles to the modeling of allelic aSTR (autosomal short tandem repeats) read counts from NGS-DNA profiles, specifically for profiles generated from the ForenSeq™ DNA Signature Prep Kit, DNA Primer Mix B. Bright et al.'s model consists of three key components within the estimation of total allelic product-template,...
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