Article
Statistical modeling of STR capillary electrophoresis signal.
BMC bioinformatics - 2 Dec 2019
Karkar Slim, Alfonse Lauren E, Grgicak Catherine M, Lun Desmond S
Abstract excerpt
BACKGROUND: In order to isolate an individual's genotype from a sample of biological material, most laboratories use PCR and Capillary Electrophoresis (CE) to construct a genetic profile based on polymorphic loci known as Short Tandem Repeats (STRs). The resulting profile consists of CE signal which contains information about the length and number of STR units amplified. For samples collected from the...
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