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Comparison of massively parallel sequencing to capillary electrophoresis for short tandem repeat genotyping of trace DNA.

Electrophoresis - 1 Mar 2024

Dierig Lisa, Kunz Sebastian N, Wiegand Peter

Abstract excerpt

In forensic genetics, massively parallel sequencing (MPS) offers several advantages over the current golden standard, capillary electrophoresis (CE): additional sequence information, shorter amplicon lengths, and the simultaneous analysis of many markers. These benefits result in a reduced number of reactions necessary while improving the amount of data obtained, thereby conserving valuable sample extracts. This...

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PMID: 38085164
DOI: 10.1002/elps.202300145

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