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Article

Patatin-like phosphatase domain-containing 3 genotype and quality of dietary fat modify the liver adiposity in men.

European journal of nutrition - 29 Jun 2026

Tauriainen Milla-M, Lankinen Maria A, Hakumäki Juhana M, Lahtinen Olli M, Husso Minna, Ågren Jyrki J, Laakso Markku, Schwab Ursula S

Abstract excerpt

BACKGROUND: Patatin-like phosphatase domain-containing 3 (PNPLA3) gene and dietary fat are important factors for metabolic dysfunction-associated steatotic liver disease (MASLD). OBJECTIVE: We studied the impact of dietary fat quality modification on liver adiposity in men homozygotes for PNPLA3 (GG, carriers of the risk allele and CC, non-carriers). METHODS: Ninety-eight men (age: 67.8 ± 4.2 years, body mass...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42371130
DOI: 10.1007/s00394-026-04031-6
PMCID: PMC13314847

Genes

PNPLA3

Variants

rs738409

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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