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Article

Preliminary Evidence for Sex Differences in CYP2C19 Metabolic Capacity During Psychotropic Drug Treatment.

Genes - 21 Jun 2026

Eiberger Janina, Weber Heike, Reif Andreas, Deckert Jürgen, Walther Sebastian, Hahn Martina, Scherf-Clavel Maike

Abstract excerpt

Background/Objectives: Sex-specific differences in the pharmacokinetics of psychotropic drugs are gaining increasing clinical relevance, but only limited data are currently available on sex-specific effects within genetically defined metabolizer phenotype categories. The objective of this study was to assess genotype-dependent sex differences in the metabolic capacity of the drug-metabolizing enzymes CYP2D6 and...

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Share to Cytochrome P-450 CYP2C19
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 42353876
DOI: 10.3390/genes17060718
PMCID: PMC13299576

Genes

CYP2C19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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