Article
Sex-specific differences in CYP450 isoforms in humans.
Expert opinion on drug metabolism & toxicology - 1 Apr 2008
Scandlyn Marissa J, Stuart Emma C, Rosengren Rhonda J
Abstract excerpt
BACKGROUND: The activity of various CYP isoforms is critical for maintaining the clinical effectiveness of many medications. Therefore, determining the sex-dependent activity of clinically relevant CYP families is highly important for optimal therapeutic effectiveness. OBJECTIVE: This review examined the sex-dependent activity of CYP3A, CYP1A2, CYP2D6, CYP2C9, CYP2C19 and CYP2E1. METHODS: This review searched for...
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