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Article

Swiss cheese Is Essential for Maintaining Spermatogenesis and the Proper Functioning of Biological Barriers in Drosophila.

International journal of molecular sciences - 17 Jun 2026

Ryabova Elena V, Ivanova Ekaterina A, Komissarov Artem E, Bolobolova Elena U, Dorogova Natalia V, Slepneva Elizaveta E, Latypova Evgenia M, Ogneva Irina V, Sarantseva Svetlana V

Abstract excerpt

Functional changes in PNPLA6 (Patatin-like phospholipase domain-containing protein 6), caused by gene mutations or inhibition by organophosphates, affect the levels of various phospholipids. In humans, this leads to organophosphorus compound-induced delayed neurotoxicity syndrome (OPIDN) and a number of rare diseases. In this study, we analyze the role of the Swiss cheese gene (sws), an ortholog of PNPLA6, in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42353202
DOI: 10.3390/ijms27125486
PMCID: PMC13299251

Genes

PNPLA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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