Article
Egg Yolk Antibodies Elicited by a Novel Multi-Epitope Recombinant Adenovirus Vaccine Against Genotype G2b PEDV Spike Protein Reduce Mortality and Viral Shedding in Passively Immunized Piglets.
Pathogens (Basel, Switzerland) - 3 Jun 2026
Qiu Cunyi, Zhou Zhiding, Yang Meilin, Wang Huaxin, Li Xuezhao, Feng Zhihua, Zhou Yefei
Abstract excerpt
Porcine epidemic diarrhea (PED), caused by the PED virus (PEDV), remains one of the most devastating diseases in the swine industry, with a mortality rate approaching 90-100% in suckling piglets due to severe dehydration and electrolyte imbalances. Passive immunization with egg yolk antibodies (IgY) represents a promising therapeutic strategy. In this study, we developed a novel recombinant adenovirus,...
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