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Epitopes screening and vaccine molecular design of PEDV S protein based on immunoinformatics

22 Aug 2024

Abstract excerpt

Porcine epidemic diarrhea virus (PEDV) is a serious disease that poses a significant threat to the pig industry. This study focused on analyzing the Spike protein of PEDV, which harbors crucial antigenic determinants, in identifying dominant epitopes. Immunoinformatics tools were used to screen for B-cell, CD4+ and CD8+ predominance epitopes. These epitopes were then connected to the N-terminal of ferritin to...

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PMID: 39174674
DOI: 10.1038/s41598-024-70579-0

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