Article
A more complete picture: capturing single nucleotide variant diversity in extended-spectrum beta-lactamase producing Escherichia coli using post-enrichment metagenomics.
Microbial genomics - 1 Jun 2026
Gallichan Sarah, Mäklin Tommi, Picton-Barlow Esther, McKeown Claudia, Forrest Sally, Corander Jukka, Moore Maria, Feasey Nicholas A, Heinz Eva, Graf Fabrice E, Lewis Joseph M
Abstract excerpt
Inferring transmission relies on accurately distinguishing between isolates from the same source and those from different sources, and high-quality genomic data are frequently used to model transmission scenarios. The post-enrichment metagenome sequencing (pe-MGS) method uses a sequencing approach to analyse the diversity of a target pathogen enriched by pre-culturing and has been effectively used to analyse the...
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