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Article

Variation in TP63 is associated with lung adenocarcinoma in the UK population.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2011

Wang Yufei, Broderick Peter, Matakidou Athena, Vijayakrishnan Jayaram, Eisen Timothy, Houlston Richard S

Abstract excerpt

BACKGROUND: Variation at TP63 has recently been shown to be associated with lung adenocarcinoma in the Asian population. METHODS: To investigate how this finding translates to the European population we compared the genotypes of SNPs annotating the TP63 locus at 3q28 in 4,462 lung cancer patients, including 911 with adenocarcinoma, and 8,235 controls from the United Kingdom. RESULTS: A statistically significant...

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PMID: 21610222
DOI: 10.1158/1055-9965.EPI-11-0042
PMCID: PMC5108419

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