Article
Whole-Exome Sequencing Reveals Uncaptured Variation and Distinct Ancestry in the Southern African Population of Botswana.
American journal of human genetics - 3 May 2018
Retshabile Gaone, Mlotshwa Busisiwe C, Williams Lesedi, Mwesigwa Savannah, Mboowa Gerald, Huang Zhuoyi, Rustagi Navin, Swaminathan Shanker, Katagirya Eric, Kyobe Samuel, Wayengera Misaki, Kisitu Grace P, Kateete David P, Wampande Eddie M, Maplanka Koketso, Kasvosve Ishmael, Pettitt Edward D, Matshaba Mogomotsi, Nsangi Betty, Marape Marape, Tsimako-Johnstone Masego, Brown Chester W, Yu Fuli, Kekitiinwa Adeodata, Joloba Moses, Mpoloka Sununguko W, Mardon Graeme, Anabwani Gabriel, Hanchard Neil A
Abstract excerpt
Large-scale, population-based genomic studies have provided a context for modern medical genetics. Among such studies, however, African populations have remained relatively underrepresented. The breadth of genetic diversity across the African continent argues for an exploration of local genomic context to facilitate burgeoning disease mapping studies in Africa. We sought to characterize genetic variation and to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.