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Article

Identification of high-risk SNPs in SLC22A transporter genes: their potential role in PCOS and metformin uptake.

BMC genomic data - 17 Jun 2026

Harini R, Usha B, Satish R, Akshatha Pai, Vijaya Kumar T M

Abstract excerpt

Polycystic ovary syndrome is a prevalent, heterogeneous endocrine and metabolic disorder affecting approximately 10% of women of reproductive age, often characterized by hyperandrogenism, anovulation, and insulin resistance. Metformin, a first-line treatment for type 2 diabetes, is also widely prescribed for PCOS to reduce insulin resistance and induce ovulation. However, therapeutic response varies significantly...

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Share to Organic Cation Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42310538
DOI: 10.1186/s12863-026-01424-8
PMCID: PMC13277229

Genes

SLC22A1
SLC22A2
SLC22A3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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